Probabilistic Neural Networks for Multi-class Tissue Discrimination with Gene Expression Data

Rui Xu; Donald C. Wunsch

doi:10.1109/IJCNN.2003.1223662

Probabilistic Neural Networks for Multi-class Tissue Discrimination with Gene Expression Data

Rui Xu
, Donald C. Wunsch

Missouri University of Science and Technology

Research output: Contribution to journal › Article › peer-review

Abstract

With the emergence and rapid advancement of DNA microarray technologies, construction of gene expression profiles for different cancer types has already become a promising means for cancer diagnosis and treatment. Most previous research has focused on binary classification. Here, we use a probabilistic neural network (PNN) for multi-classification of cancer data. The experimental results demonstrate the effectiveness of the PNN in addressing gene expression data.

Original language	American English
Journal	Proceedings of the International Joint Conference on Neural Networks, 2003
DOIs	https://doi.org/10.1109/IJCNN.2003.1223662
State	Published - Jan 1 2003

Keywords

Binary Classification
Cancer
Cancer Data
Cancer Diagnosis
Cancer Treatment
DNA
DNA Microarray Technologies
Deoxyribonucleic Acid
Gene Expression Data
Gene Expression Profiles
Medical Computing
Multiclass Tissue Discrimination
Neural Nets
Pattern Classification
Probabilistic Neural Networks
Probability

Disciplines

Electrical and Computer Engineering

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Cite this

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title = "Probabilistic Neural Networks for Multi-class Tissue Discrimination with Gene Expression Data",

abstract = " With the emergence and rapid advancement of DNA microarray technologies, construction of gene expression profiles for different cancer types has already become a promising means for cancer diagnosis and treatment. Most previous research has focused on binary classification. Here, we use a probabilistic neural network (PNN) for multi-classification of cancer data. The experimental results demonstrate the effectiveness of the PNN in addressing gene expression data.",

keywords = "Binary Classification, Cancer, Cancer Data, Cancer Diagnosis, Cancer Treatment, DNA, DNA Microarray Technologies, Deoxyribonucleic Acid, Gene Expression Data, Gene Expression Profiles, Medical Computing, Multiclass Tissue Discrimination, Neural Nets, Pattern Classification, Probabilistic Neural Networks, Probability",

author = "Rui Xu and Wunsch, \{Donald C.\}",

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language = "American English",

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AU - Wunsch, Donald C.

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N2 - With the emergence and rapid advancement of DNA microarray technologies, construction of gene expression profiles for different cancer types has already become a promising means for cancer diagnosis and treatment. Most previous research has focused on binary classification. Here, we use a probabilistic neural network (PNN) for multi-classification of cancer data. The experimental results demonstrate the effectiveness of the PNN in addressing gene expression data.

AB - With the emergence and rapid advancement of DNA microarray technologies, construction of gene expression profiles for different cancer types has already become a promising means for cancer diagnosis and treatment. Most previous research has focused on binary classification. Here, we use a probabilistic neural network (PNN) for multi-classification of cancer data. The experimental results demonstrate the effectiveness of the PNN in addressing gene expression data.

KW - Binary Classification

KW - Cancer

KW - Cancer Data

KW - Cancer Diagnosis

KW - Cancer Treatment

KW - DNA

KW - DNA Microarray Technologies

KW - Deoxyribonucleic Acid

KW - Gene Expression Data

KW - Gene Expression Profiles

KW - Medical Computing

KW - Multiclass Tissue Discrimination

KW - Neural Nets

KW - Pattern Classification

KW - Probabilistic Neural Networks

KW - Probability

UR - https://scholarsmine.mst.edu/ele_comeng_facwork/1838

U2 - 10.1109/IJCNN.2003.1223662

DO - 10.1109/IJCNN.2003.1223662

M3 - Article

JO - Proceedings of the International Joint Conference on Neural Networks, 2003

JF - Proceedings of the International Joint Conference on Neural Networks, 2003

ER -

Probabilistic Neural Networks for Multi-class Tissue Discrimination with Gene Expression Data

Abstract

Keywords

Disciplines

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