One-year chronic toxicity evaluation of single dose intravenously administered silica nanoparticles in mice and their Ex vivo human hemocompatibility

Raziye Mohammadpour; Darwin L. Cheney; Jason W. Grunberger; Mostafa Yazdimamaghani; Jolanta Jedrzkiewicz; Kyle J. Isaacson; Marina A. Dobrovolskaia; Hamidreza Ghandehari

doi:10.1016/j.jconrel.2020.05.027

One-year chronic toxicity evaluation of single dose intravenously administered silica nanoparticles in mice and their Ex vivo human hemocompatibility

Raziye Mohammadpour
, Darwin L. Cheney
, Jason W. Grunberger
, Mostafa Yazdimamaghani
, Jolanta Jedrzkiewicz
, Kyle J. Isaacson
, Marina A. Dobrovolskaia
, Hamidreza Ghandehari

University of Utah
Department of Pharmaceutics and Pharmaceutical Chemistry
Leidos Inc

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	471-481
Number of pages	11
Journal	Journal of Controlled Release
Volume	324
DOIs	https://doi.org/10.1016/j.jconrel.2020.05.027
State	Published - Aug 10 2020
Externally published	Yes

ASJC Scopus Subject Areas

Pharmaceutical Science

Keywords

BALB/c mice
Chronic toxicity
Complement
Hemocompatibility
Nanotoxicology
One-year
Porosity
Silica nanoparticles

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10.1016/j.jconrel.2020.05.027

Cite this

Mohammadpour, R., Cheney, D. L., Grunberger, J. W., Yazdimamaghani, M., Jedrzkiewicz, J., Isaacson, K. J., Dobrovolskaia, M. A., & Ghandehari, H. (2020). One-year chronic toxicity evaluation of single dose intravenously administered silica nanoparticles in mice and their Ex vivo human hemocompatibility. Journal of Controlled Release, 324, 471-481. https://doi.org/10.1016/j.jconrel.2020.05.027

Mohammadpour, R, Cheney, DL, Grunberger, JW, Yazdimamaghani, M, Jedrzkiewicz, J, Isaacson, KJ, Dobrovolskaia, MA & Ghandehari, H 2020, 'One-year chronic toxicity evaluation of single dose intravenously administered silica nanoparticles in mice and their Ex vivo human hemocompatibility', Journal of Controlled Release, vol. 324, pp. 471-481. https://doi.org/10.1016/j.jconrel.2020.05.027

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title = "One-year chronic toxicity evaluation of single dose intravenously administered silica nanoparticles in mice and their Ex vivo human hemocompatibility",

keywords = "BALB/c mice, Chronic toxicity, Complement, Hemocompatibility, Nanotoxicology, One-year, Porosity, Silica nanoparticles",

author = "Raziye Mohammadpour and Cheney, \{Darwin L.\} and Grunberger, \{Jason W.\} and Mostafa Yazdimamaghani and Jolanta Jedrzkiewicz and Isaacson, \{Kyle J.\} and Dobrovolskaia, \{Marina A.\} and Hamidreza Ghandehari",

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year = "2020",

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doi = "10.1016/j.jconrel.2020.05.027",

language = "English",

volume = "324",

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journal = "Journal of Controlled Release",

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T1 - One-year chronic toxicity evaluation of single dose intravenously administered silica nanoparticles in mice and their Ex vivo human hemocompatibility

AU - Mohammadpour, Raziye

AU - Cheney, Darwin L.

AU - Grunberger, Jason W.

AU - Yazdimamaghani, Mostafa

AU - Jedrzkiewicz, Jolanta

AU - Isaacson, Kyle J.

AU - Dobrovolskaia, Marina A.

AU - Ghandehari, Hamidreza

PY - 2020/8/10

Y1 - 2020/8/10

KW - BALB/c mice

KW - Chronic toxicity

KW - Complement

KW - Hemocompatibility

KW - Nanotoxicology

KW - One-year

KW - Porosity

KW - Silica nanoparticles

UR - https://www.scopus.com/pages/publications/85085732854

UR - https://www.scopus.com/pages/publications/85085732854#tab=citedBy

U2 - 10.1016/j.jconrel.2020.05.027

DO - 10.1016/j.jconrel.2020.05.027

M3 - Article

C2 - 32464151

AN - SCOPUS:85085732854

SN - 0168-3659

VL - 324

SP - 471

EP - 481

JO - Journal of Controlled Release

JF - Journal of Controlled Release

ER -

One-year chronic toxicity evaluation of single dose intravenously administered silica nanoparticles in mice and their Ex vivo human hemocompatibility

ASJC Scopus Subject Areas

Keywords

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