Influence of Oxygen Microenvironment on Microfluidic Glucose Sensor Performance

Chang-Soo Kim; Jongwon Park

doi:10.1109/MMB.2005.1548374

Influence of Oxygen Microenvironment on Microfluidic Glucose Sensor Performance

Chang-Soo Kim
, Jongwon Park

Electrical and Computer Engineering

Research output: Contribution to journal › Article › peer-review

Abstract

We propose a novel method to overcome significant problems of baseline drift and sensitivity degradation in amperometric biosensors based on oxidase enzyme reactions. A novel glucose microsensor with a built-in electrochemical oxygen manipulation microsystem is introduced to demonstrate three novel functionalities; one-point in situ self-calibration (zero-point), broadening of dynamic range and increase in sensitivity. The influence of electrochemically generated oxygen microenvironment on the sensor output within a fluidic structure is investigated.

Original language	American English
Journal	Proceedings of the 3rd IEEE/EMBS Special Topic Conference on Microtechnology in Medicine and Biology, 2005
DOIs	https://doi.org/10.1109/MMB.2005.1548374
State	Published - Jan 1 2005

Keywords

Electrolysis
Hydrogen
Oxygen

Disciplines

Biology
Electrical and Computer Engineering

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Influence of Oxygen Microenvironment on Microfluidic Glucose SensFinal published version, 1.07 MBLicense: Unspecified

Cite this

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title = "Influence of Oxygen Microenvironment on Microfluidic Glucose Sensor Performance",

abstract = " We propose a novel method to overcome significant problems of baseline drift and sensitivity degradation in amperometric biosensors based on oxidase enzyme reactions. A novel glucose microsensor with a built-in electrochemical oxygen manipulation microsystem is introduced to demonstrate three novel functionalities; one-point in situ self-calibration (zero-point), broadening of dynamic range and increase in sensitivity. The influence of electrochemically generated oxygen microenvironment on the sensor output within a fluidic structure is investigated.",

keywords = "Electrolysis, Hydrogen, Oxygen",

author = "Chang-Soo Kim and Jongwon Park",

year = "2005",

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N2 - We propose a novel method to overcome significant problems of baseline drift and sensitivity degradation in amperometric biosensors based on oxidase enzyme reactions. A novel glucose microsensor with a built-in electrochemical oxygen manipulation microsystem is introduced to demonstrate three novel functionalities; one-point in situ self-calibration (zero-point), broadening of dynamic range and increase in sensitivity. The influence of electrochemically generated oxygen microenvironment on the sensor output within a fluidic structure is investigated.

AB - We propose a novel method to overcome significant problems of baseline drift and sensitivity degradation in amperometric biosensors based on oxidase enzyme reactions. A novel glucose microsensor with a built-in electrochemical oxygen manipulation microsystem is introduced to demonstrate three novel functionalities; one-point in situ self-calibration (zero-point), broadening of dynamic range and increase in sensitivity. The influence of electrochemically generated oxygen microenvironment on the sensor output within a fluidic structure is investigated.

KW - Electrolysis

KW - Hydrogen

KW - Oxygen

UR - https://scholarsmine.mst.edu/ele_comeng_facwork/712

U2 - 10.1109/MMB.2005.1548374

DO - 10.1109/MMB.2005.1548374

M3 - Article

JO - Proceedings of the 3rd IEEE/EMBS Special Topic Conference on Microtechnology in Medicine and Biology, 2005

JF - Proceedings of the 3rd IEEE/EMBS Special Topic Conference on Microtechnology in Medicine and Biology, 2005

ER -

Influence of Oxygen Microenvironment on Microfluidic Glucose Sensor Performance

Abstract

Keywords

Disciplines

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