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Increased Nuclear Ploidy, Not Cell Proliferation, Is Sustained in the Peroxisome Proliferator-Treated Rat Liver

  • Narendra D. Lalwani
  • , Lloyd A. Dethloff
  • , Jeffrey R. Haskins
  • , Donald G. Robertson
  • , Felix A. de la Iglesia
  • Pfizer

Research output: Contribution to journal › Article › peer-review

Original languageEnglish
Pages (from-to)165-176
Number of pages12
JournalToxicologic Pathology
Volume25
Issue number2
DOIs
StatePublished - Mar 1997
Externally publishedYes

ASJC Scopus Subject Areas

  • Pathology and Forensic Medicine
  • Molecular Biology
  • Toxicology
  • Cell Biology

Keywords

  • Bromodeoxyuridine incorporation
  • cell-cycle analysis
  • DNA synthesis
  • hepatocarcinogenesis
  • hypolipidemic compounds
  • nongenotoxic carcinogens
  • peroxisomes
  • proliferating cell nuclear antigen
  • S phase
  • Wy-14,643

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