Abstract
Silicate-based bioactive glasses undergo incomplete conversion to a calcium phosphate material after in vivo implantation, which severely limits their biomedical application. In this communication, novel borate-based glasses with controllable degradation behavior were developed and their bioactive potential was investigated in vitro. when immersed in a 0.02M K2HPO4 solution at 37°C, these glasses reacted to form a carbonate-substituted hydroxyapatite (c-HA) on their surfaces, indicating their bioactive potential. The conversion rate to c-HA was controlled by adjusting the B2O3/SiO2 ratio in the glass composition. The results indicate the potential application of the borate-based bioactive glass as scaffold materials for bone tissue engineering.
| Original language | American English |
|---|---|
| Pages (from-to) | 303-306 |
| Number of pages | 4 |
| Journal | Journal of the American Ceramic Society |
| Volume | 90 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 1 2007 |
Keywords
- Bioactive Glasses
- Biomedical Application
- Controllable Degradation
Disciplines
- Materials Science and Engineering
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