Correlations between Molecular Numbers and Molecular Masses in an Evanescent Field and their Applications in Probing Molecular Interactions

Hongwei Gai; Qi Wang; Yinfa Ma; Bingcheng Lin

doi:10.1002/ange.200500461

Correlations between Molecular Numbers and Molecular Masses in an Evanescent Field and their Applications in Probing Molecular Interactions

Hongwei Gai
, Qi Wang
, Yinfa Ma
, Bingcheng Lin

Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

Complex numbers: The number of molecules detected in the evanescent field during single-molecule fluorescence imaging decreases with increasing molecular weight in free solution (see graphic; FITC = fluorescein isothiocyanate). This technique could be useful for screening undefined molecular interactions at extremely low concentrations without separation.

Original language	American English
Journal	Angewandte Chemie International Edition
Volume	44
DOIs	https://doi.org/10.1002/ange.200500461
State	Published - Aug 1 2005

Keywords

Evanescent Field
Fluorescence
Molecule Counting
Oligonucleotides
Single-molecule Studies

Disciplines

Chemistry

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10.1002/ange.200500461License: Unspecified

https://doi.org/10.1002/ange.200500461

Cite this

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title = "Correlations between Molecular Numbers and Molecular Masses in an Evanescent Field and their Applications in Probing Molecular Interactions",

abstract = " Complex numbers: The number of molecules detected in the evanescent field during single-molecule fluorescence imaging decreases with increasing molecular weight in free solution (see graphic; FITC = fluorescein isothiocyanate). This technique could be useful for screening undefined molecular interactions at extremely low concentrations without separation.",

keywords = "Evanescent Field, Fluorescence, Molecule Counting, Oligonucleotides, Single-molecule Studies",

author = "Hongwei Gai and Qi Wang and Yinfa Ma and Bingcheng Lin",

year = "2005",

month = aug,

day = "1",

doi = "10.1002/ange.200500461",

language = "American English",

volume = "44",

journal = "Angewandte Chemie International Edition",

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TY - JOUR

T1 - Correlations between Molecular Numbers and Molecular Masses in an Evanescent Field and their Applications in Probing Molecular Interactions

AU - Gai, Hongwei

AU - Wang, Qi

AU - Ma, Yinfa

AU - Lin, Bingcheng

PY - 2005/8/1

Y1 - 2005/8/1

N2 - Complex numbers: The number of molecules detected in the evanescent field during single-molecule fluorescence imaging decreases with increasing molecular weight in free solution (see graphic; FITC = fluorescein isothiocyanate). This technique could be useful for screening undefined molecular interactions at extremely low concentrations without separation.

AB - Complex numbers: The number of molecules detected in the evanescent field during single-molecule fluorescence imaging decreases with increasing molecular weight in free solution (see graphic; FITC = fluorescein isothiocyanate). This technique could be useful for screening undefined molecular interactions at extremely low concentrations without separation.

KW - Evanescent Field

KW - Fluorescence

KW - Molecule Counting

KW - Oligonucleotides

KW - Single-molecule Studies

UR - https://scholarsmine.mst.edu/chem_facwork/10

UR - https://doi.org/10.1002/ange.200500461

U2 - 10.1002/ange.200500461

DO - 10.1002/ange.200500461

M3 - Article

SN - 1521-3773

VL - 44

JO - Angewandte Chemie International Edition

JF - Angewandte Chemie International Edition

ER -

Correlations between Molecular Numbers and Molecular Masses in an Evanescent Field and their Applications in Probing Molecular Interactions

Abstract

Keywords

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