Anticoagulant-Related Intracerebral Hemorrhage

Carlos S. Kase; R. Kent Robinson; Robert W. Stein; L. Dana DeWitt; Daniel B. Hier; Daryl L. Harp; J. Powell Williams; Louis R. Caplan; J. P. Mohr

doi:10.1212/wnl.35.7.943

Anticoagulant-Related Intracerebral Hemorrhage

Carlos S. Kase
, R. Kent Robinson
, Robert W. Stein
, L. Dana DeWitt
, Daniel B. Hier
, Daryl L. Harp
, J. Powell Williams
, Louis R. Caplan
, J. P. Mohr

Electrical and Computer Engineering

Research output: Contribution to journal › Article › peer-review

Abstract

Twenty-Four Patients Had Intracerebral Hemorrhage While They Were Being Treated with Anticoagulants. Hypertension Was Present in 67% of the Cases, Head Trauma Was an Uncommon Preceding Event, and Simultaneous Bleeding in Other Organs Occurred in Only One Instance. Neurologic Abnormalities Progressed for Several Hours in 58%. Seizures Occurred at Onset in 12.5%. the Location of the Hemorrhage Was as Follows: Cerebellum (Nine Cases), Lobar White Matter (Six), Basal Ganglia (Five), Thalamus (Two), and Hemisphere, Unspecified (Two). in 61%, the Hemorrhages Occurred within 6 Months of Therapy. in 75%, the Prothrombin Time Was Beyond 1½ Times the Control Value. Mortality Was 62.5%. Survivors Had Smaller Hematomas Than Did Patients with Fatal Hemorrhage. © 1985 American Academy of Neurology.

Original language	American English
Journal	Neurology
Volume	35
DOIs	https://doi.org/10.1212/wnl.35.7.943
State	Published - Jan 1 1985

Disciplines

Chemistry

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https://doi.org/10.1212/wnl.35.7.943

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@article{bf1b93b52aa44aa480c53326601c31e5,

title = "Anticoagulant-Related Intracerebral Hemorrhage",

abstract = " Twenty-Four Patients Had Intracerebral Hemorrhage While They Were Being Treated with Anticoagulants. Hypertension Was Present in 67\% of the Cases, Head Trauma Was an Uncommon Preceding Event, and Simultaneous Bleeding in Other Organs Occurred in Only One Instance. Neurologic Abnormalities Progressed for Several Hours in 58\%. Seizures Occurred at Onset in 12.5\%. the Location of the Hemorrhage Was as Follows: Cerebellum (Nine Cases), Lobar White Matter (Six), Basal Ganglia (Five), Thalamus (Two), and Hemisphere, Unspecified (Two). in 61\%, the Hemorrhages Occurred within 6 Months of Therapy. in 75\%, the Prothrombin Time Was Beyond 1½ Times the Control Value. Mortality Was 62.5\%. Survivors Had Smaller Hematomas Than Did Patients with Fatal Hemorrhage. {\textcopyright} 1985 American Academy of Neurology.",

author = "Kase, \{Carlos S.\} and Robinson, \{R. Kent\} and Stein, \{Robert W.\} and DeWitt, \{L. Dana\} and Hier, \{Daniel B.\} and Harp, \{Daryl L.\} and Williams, \{J. Powell\} and Caplan, \{Louis R.\} and Mohr, \{J. P.\}",

year = "1985",

month = jan,

day = "1",

doi = "10.1212/wnl.35.7.943",

language = "American English",

volume = "35",

journal = "Neurology",

}

TY - JOUR

T1 - Anticoagulant-Related Intracerebral Hemorrhage

AU - Kase, Carlos S.

AU - Robinson, R. Kent

AU - Stein, Robert W.

AU - DeWitt, L. Dana

AU - Hier, Daniel B.

AU - Harp, Daryl L.

AU - Williams, J. Powell

AU - Caplan, Louis R.

AU - Mohr, J. P.

PY - 1985/1/1

Y1 - 1985/1/1

N2 - Twenty-Four Patients Had Intracerebral Hemorrhage While They Were Being Treated with Anticoagulants. Hypertension Was Present in 67% of the Cases, Head Trauma Was an Uncommon Preceding Event, and Simultaneous Bleeding in Other Organs Occurred in Only One Instance. Neurologic Abnormalities Progressed for Several Hours in 58%. Seizures Occurred at Onset in 12.5%. the Location of the Hemorrhage Was as Follows: Cerebellum (Nine Cases), Lobar White Matter (Six), Basal Ganglia (Five), Thalamus (Two), and Hemisphere, Unspecified (Two). in 61%, the Hemorrhages Occurred within 6 Months of Therapy. in 75%, the Prothrombin Time Was Beyond 1½ Times the Control Value. Mortality Was 62.5%. Survivors Had Smaller Hematomas Than Did Patients with Fatal Hemorrhage. © 1985 American Academy of Neurology.

AB - Twenty-Four Patients Had Intracerebral Hemorrhage While They Were Being Treated with Anticoagulants. Hypertension Was Present in 67% of the Cases, Head Trauma Was an Uncommon Preceding Event, and Simultaneous Bleeding in Other Organs Occurred in Only One Instance. Neurologic Abnormalities Progressed for Several Hours in 58%. Seizures Occurred at Onset in 12.5%. the Location of the Hemorrhage Was as Follows: Cerebellum (Nine Cases), Lobar White Matter (Six), Basal Ganglia (Five), Thalamus (Two), and Hemisphere, Unspecified (Two). in 61%, the Hemorrhages Occurred within 6 Months of Therapy. in 75%, the Prothrombin Time Was Beyond 1½ Times the Control Value. Mortality Was 62.5%. Survivors Had Smaller Hematomas Than Did Patients with Fatal Hemorrhage. © 1985 American Academy of Neurology.

UR - https://scholarsmine.mst.edu/chem_facwork/3338

UR - https://doi.org/10.1212/wnl.35.7.943

U2 - 10.1212/wnl.35.7.943

DO - 10.1212/wnl.35.7.943

M3 - Article

C2 - 4010961

VL - 35

JO - Neurology

JF - Neurology

ER -

Anticoagulant-Related Intracerebral Hemorrhage

Abstract

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